Saroj Khadka

prof_pic.jpg

Greetings! I am a PhD Candidate at the University of Pittsburgh, working under the supervision of Dr. Laura A. Mike. My research in the Mike Lab (themikelab.com) focuses on the molecular mechanisms and regulation of capsular polysaccharide–associated phenotypes in Klebsiella pneumoniae, particularly those linked to bacterial fitness and virulence.

Prior to joining the PhD program, I earned an MS in Medical Microbiology (2019) and a BS in Microbiology (2016) from Tribhuvan University, Nepal. I also have experience as a medical microbiologist in clinical diagnostic settings. My research expertise spans molecular microbiology, bacterial genetics, high-throughput phenotypic screening, polysaccharide biochemistry, and protein structure–function analysis. I am particularly skilled in dissecting regulatory networks that control bacterial virulence traits, integrating experimental and computational approaches to better understand pathogen behavior and adaptation.

News

Jan 05, 2026 Excited to launch my personal website created using al-folio theme available on GitHub. This website is not fully updated yet.

Latest Posts

Selected Publications

  1. Antimicrobial resistance in Salmonella Typhi isolated from a referral Hospital of Kathmandu, Nepal
    Saroj Khadka, Basudha Shrestha, Anil Pokhrel, and 3 more authors
    Microbiology insights, 2021
  2. Urine-mediated suppression of Klebsiella pneumoniae mucoidy is counteracted by spontaneous Wzc variants altering capsule chain length
    Saroj Khadka, Brooke E Ring, Ryan S Walker, and 5 more authors
    Msphere, 2023
  3. Arginine regulates the mucoid phenotype of hypervirulent Klebsiella pneumoniae
    Brooke E Ryan, Caitlyn L Holmes, Drew J Stark, and 6 more authors
    Nature Communications, 2025
  4. Sugar Import Suppresses Klebsiella pneumoniae Mucoidy in cAMP-CRP-dependent Manner
    Saroj Khadka, Gabriella Gates, Drew J Stark, and 2 more authors
    bioRxiv, 2025